Structure of PDB 5dag Chain A

Receptor sequence
>5dagA (length=171) Species: 9606 (Homo sapiens) [Search protein sequence]
GCCVCSDERGWAENPLVYCDGHGCSVAVHQACYGIVQVPTGPWFCRKCES
QERAARVRCELCPHKDGALKRTDNGGWAHVVCALYIPEVQFANVSTMEPI
VLQSVPHDRYNKTCYICDEQGRESKAATGACMTCNKHGCRQAFHVTCAQF
AGLLCQYCGYCKYHFSKLKKS
3D structure
PDB5dag The PZP Domain of AF10 Senses Unmodified H3K27 to Regulate DOT1L-Mediated Methylation of H3K79.
ChainA
Resolution1.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN A C25 C28 H52 C55 C2 C5 H29 C32
BS02 ZN A C157 C162 C194 H197 C134 C139 C161 H164
BS03 ZN A C137 C140 H167 C170 C114 C117 H144 C147
BS04 ZN A C82 C85 H102 C105 C59 C62 H79 C82
BS05 ZN A C42 C47 C68 C71 C19 C24 C45 C48
External links
PDB RCSB:5dag, PDBe:5dag, PDBj:5dag
PDBsum5dag
PubMed26439302
UniProtP55197|AF10_HUMAN Protein AF-10 (Gene Name=MLLT10)

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