Structure of PDB 5daf Chain A

Receptor sequence
>5dafA (length=121) Species: 9606 (Homo sapiens) [Search protein sequence]
RTFSYTLEDHTKQAFGIMNELRLSQQLCDVTLQVKYQDAPAAQFMAHKVV
LASSSPVFKAMFTMEVVSIEGIHPKVMERLIEFAYTASISMGEKCVLHVM
NGAVMYQIDSVVRACSDFLVQ
3D structure
PDB5daf Characterization of novel small-molecule NRF2 activators: Structural and biochemical validation of stereospecific KEAP1 binding.
ChainA
Resolution2.37 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 58E A Y85 K131 M147 G148 K150 C151 H154 Y36 K75 M91 G92 K94 C95 H98
External links
PDB RCSB:5daf, PDBe:5daf, PDBj:5daf
PDBsum5daf
PubMed27474998
UniProtQ14145|KEAP1_HUMAN Kelch-like ECH-associated protein 1 (Gene Name=KEAP1)

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