Structure of PDB 5dac Chain A

Receptor sequence
>5dacA (length=432) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence]
SKIEKLSILGVRSFGPHHPETIAFNTPLTLIVGYNGSGKTTVIECLKYAT
TGELPPNSTRNGAFIHDPDLVGEKEVRAQVKLSFRSTIGESYVVTRNIQL
LVQRNNKRTQKTLEGSLLLRNNGERTVISTRVAELDKLVSEKLGVPPAIL
DAVIFCHQDDSLWPMSEPAALKKRFDEIFEAQKYTKVIENIRLLKKKKGD
ELKILKEREVQDKANKERAEDLKDAKAKYKETHIKVETTKAAIEDLGRGM
AAVDHAIMQYHSKMMEQINRTIAELWQSTYQGTDIDTIQIRSDVESTTSS
DSGTRRNYNYRVSMVKGDTEMDMRGRCSAGQKVLASIIIRLALAESFCAN
CGLIALDQPTTNLDSDNIRSLAESLHGIIKARQAQGNLQLIVITHDEEFL
KYMQCSDFCDDFYRVKRDEKQNSVIVRESITR
3D structure
PDB5dac Structural mechanism of ATP-dependent DNA binding and DNA end bridging by eukaryotic Rad50.
ChainA
Resolution2.503 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A R61 T110 Q111 K112 T113 R60 T109 Q110 K111 T112
BS02 MG A T41 Q159 T40 Q158
BS03 AGS A R13 S14 N36 G37 G39 K40 T41 T42 A64 H1275 R1297 R12 S13 N35 G36 G38 K39 T40 T41 A63 H395 R417
BS04 AES A E1225 R1262 E345 R382
BS05 AGS A M1194 R1206 S1208 A1209 G1210 Q1211 M314 R326 S328 A329 G330 Q331
Gene Ontology
Molecular Function
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0006302 double-strand break repair

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Molecular Function
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Biological Process
External links
PDB RCSB:5dac, PDBe:5dac, PDBj:5dac
PDBsum5dac
PubMed26896444
UniProtG0SHW7|RAD50_CHATD DNA repair protein RAD50 (Gene Name=RAD50)

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