Structure of PDB 5d8u Chain A

Receptor sequence
>5d8uA (length=179) Species: 641501 (Influenza A virus (A/California/04/2009(H1N1))) [Search protein sequence]
GSHMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFM
YSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENR
FIDIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEE
SRARIKTRLFTIRQEMASRSLWDSFRQSE
3D structure
PDB5d8u Identification and characterization of influenza variants resistant to a viral endonuclease inhibitor.
ChainA
Resolution2.29 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN A H41 D108 D119 I120 H44 D92 D103 I104
BS02 MN A E80 D108 E64 D92
BS03 0N8 A H41 D108 D119 K134 H44 D92 D103 K118 MOAD: Kd=949nM
Gene Ontology
Biological Process
GO:0039694 viral RNA genome replication

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Molecular Function
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Biological Process
External links
PDB RCSB:5d8u, PDBe:5d8u, PDBj:5d8u
PDBsum5d8u
PubMed26976575
UniProtC3W5S0

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