Structure of PDB 5d3z Chain A

Receptor sequence
>5d3zA (length=263) Species: 1836 (Saccharopolyspora erythraea) [Search protein sequence]
SSALRDGYRQAGVSGRVRSYLDLLAGLSDFREHFDGSDGFSLDLVDMADG
PGEVTVICCAGTAAISGPHEFTRLAGALRGIAPVRAVPQPGYEEGEPLPS
SMAAVAAVQADAVIRTQGDKPFVVAGHSAGALMAYALATELLDRGHPPRG
VVLIDVYPPQDAMNAWLEELTATLFDRETVRMDDTRLTALGAYDRLTGQW
RPRETGLPTLLVSAGEPMGPWPDDSWKPTWPFEHDTVAVPGDHFTMVQEH
ADAIARHIDAWLG
3D structure
PDB5d3z Towards a characterization of the structural determinants of specificity in the macrocyclizing thioesterase for deoxyerythronolide B biosynthesis.
ChainA
Resolution2.1 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) S142 A143 D169 H259
Catalytic site (residue number reindexed from 1) S128 A129 D155 H243
Enzyme Commision number 2.3.1.94: 6-deoxyerythronolide-B synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 57H A S142 A143 H259 S128 A129 H243
Gene Ontology
Biological Process
GO:0009058 biosynthetic process

View graph for
Biological Process
External links
PDB RCSB:5d3z, PDBe:5d3z, PDBj:5d3z
PDBsum5d3z
PubMed26592346
UniProtQ03133|ERYA3_SACER 6-deoxyerythronolide-B synthase EryA3, modules 5 and 6 (Gene Name=eryA)

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