Structure of PDB 5d3y Chain A

Receptor sequence
>5d3yA (length=136) Species: 9606 (Homo sapiens) [Search protein sequence]
ALEQLQSHIEGWEGSNLTDICTQLLLQGTLLKISAGNIQERAFFLFDNLL
VYCKRKSRVSLYIFRGRINTEVMEVENVEDGTADYHSNGYTVTNGWKIHN
TAKNKWFVCMAKTAEEKQKWLDAIIREREQRESLKL
3D structure
PDB5d3y Structural and Biochemical Characterization of the Catalytic Core of the Metastatic Factor P-Rex1 and Its Regulation by PtdIns(3,4,5)P3.
ChainA
Resolution1.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 4IP A K280 S282 N285 Q287 R289 Y300 R328 K366 K368 K32 S34 N37 Q39 R41 Y52 R65 K103 K105 MOAD: Kd=440nM
External links
PDB RCSB:5d3y, PDBe:5d3y, PDBj:5d3y
PDBsum5d3y
PubMed27150042
UniProtQ8TCU6|PREX1_HUMAN Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (Gene Name=PREX1)

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