Structure of PDB 5d3k Chain A

Receptor sequence
>5d3kA (length=269) Species: 1836 (Saccharopolyspora erythraea) [Search protein sequence]
SSALRDGYRQAGVSGRVRSYLDLLAGLSDFREHFDGSDGFSLDLVDMADG
PGEVTVICCAGTAAISGPHEFTRLAGALRGIAPVRAVPQPGYEEGEPLPS
SMAAVAAVQADAVIRTQGDKPFVVAGHSAGALMAYALATELLDRGHPPRG
VVLIDVYPPGHQDAMNAWLEELTATLFDRETVRMDDTRLTALGAYDRLTG
QWRPRETGLPTLLVSAGEPMGPWPDDSWKPTWPFEHDTVAVPGDHFTMVQ
EHADAIARHIDAWLGGGNS
3D structure
PDB5d3k Towards a characterization of the structural determinants of specificity in the macrocyclizing thioesterase for deoxyerythronolide B biosynthesis.
ChainA
Resolution1.7 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) S142 A143 D169 H259
Catalytic site (residue number reindexed from 1) S128 A129 D155 H245
Enzyme Commision number 2.3.1.94: 6-deoxyerythronolide-B synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A D49 D52 D35 D38
BS02 CA A E108 D199 E94 D185
Gene Ontology
Biological Process
GO:0009058 biosynthetic process

View graph for
Biological Process
External links
PDB RCSB:5d3k, PDBe:5d3k, PDBj:5d3k
PDBsum5d3k
PubMed26592346
UniProtQ03133|ERYA3_SACER 6-deoxyerythronolide-B synthase EryA3, modules 5 and 6 (Gene Name=eryA)

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