Structure of PDB 5czt Chain A

Receptor sequence
>5cztA (length=346) Species: 122586 (Neisseria meningitidis MC58) [Search protein sequence]
HYPTDDIKIKEVKELLPPIAHLYELPISKEASGLVHRTRQEISDLVHGRD
KRLLVIIGPCSIHDPKAALEYAERLLKLRKQYENELLIVMRVYFEKPRTT
VGWKGLINDPHLDGTFDINFGLRQARSLLLSLNNMGMPASTEFLDMITPQ
YYADLISWGAIGARTTESQVHRALASGLSCPVGFKNGTDGNLKIAIDAIG
AASHSHHFLSVTKAGHSAIVHTGGNPDCHVILRGGKEPNYDAEHVSEAAE
QLRAAGVTDKLMIDCSHANSRKDYTRQMEVAQDIAAQLEQDGGNIMGVMV
ESHLVEGRQDKPEVYGKSITDACIGWGATEELLALLAGANKKRMAR
3D structure
PDB5czt Neisseria meningitidis 3 dexy-D-arabino-heptulosonate 7-phosphate synthase Glu176Ala variant at 2.04 Angstroms resolution
ChainA
Resolution2.04 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.5.1.54: 3-deoxy-7-phosphoheptulonate synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN A C63 H270 E304 D324 C60 H267 E301 D321
BS02 PHE A Q153 A156 L181 S182 F211 S213 V223 Q150 A153 L178 S179 F208 S210 V220
Gene Ontology
Molecular Function
GO:0003849 3-deoxy-7-phosphoheptulonate synthase activity
GO:0016740 transferase activity
GO:0046872 metal ion binding
Biological Process
GO:0008652 amino acid biosynthetic process
GO:0009058 biosynthetic process
GO:0009073 aromatic amino acid family biosynthetic process
GO:0009423 chorismate biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Cellular Component
External links
PDB RCSB:5czt, PDBe:5czt, PDBj:5czt
PDBsum5czt
PubMed
UniProtQ9K169

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