Structure of PDB 5cw2 Chain A

Receptor sequence
>5cw2A (length=319) Species: 1078020 (Mycolicibacterium thermoresistibile ATCC 19527) [Search protein sequence]
TPSERSVETNGVRLRLVEAGERGDPLVVLAHGFPELAYSWRHQIPALVDA
GYHVMAPDQRGYGGSSAPEAIEAYDITRLTADLMGLLDDIGAEKAAFIGH
DWGALVVWNAALLYPDRVAAVAGLSVPPVPRSLTRPTEAFRALVGEDNFF
YILYFQEPGVADAELDGDPARTMRRMFGGLTSDPDAAHRMLQPGPAGFID
RLPEPEALPDWLTAEELDHYIAEFTRTGFTGGLNWYRNMDRNWELTEHLA
GATITAPALFLAGAADPVLGFMRPERATEVAVGPYRQVLLDGAGHWVQQE
RPQEVNAALIDFLRGLELQ
3D structure
PDB5cw2 The crystal structure of mycobacterial Epoxide Hydrolase A
ChainA
Resolution2.0 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) F35 H102 D103 W104 L126 S127 Y153 R173 Y238 D268 H297 W298
Catalytic site (residue number reindexed from 1) F33 H100 D101 W102 L124 S125 Y151 R171 Y236 D266 H295 W296
Enzyme Commision number 3.3.2.3: Transferred entry: 3.3.2.9 and 3.3.2.10.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BSU A D103 W104 L107 Y153 M178 Y238 M241 H297 D101 W102 L105 Y151 M176 Y236 M239 H295
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0016787 hydrolase activity

View graph for
Molecular Function
External links
PDB RCSB:5cw2, PDBe:5cw2, PDBj:5cw2
PDBsum5cw2
PubMed
UniProtG7CF24

[Back to BioLiP]