Structure of PDB 5csz Chain A

Receptor sequence
>5cszA (length=212) Species: 9606 (Homo sapiens) [Search protein sequence]
VELVESGGGLVQPGGSLRLSCAASGFTFSSYAMSWVRQAPGKGLEWVSAI
NASGTRTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCARGKG
YVRYFDVWGQGTLVTVSSASTKGPSVFPLAPSTAALGCLVKDYFPEPVTV
SWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKP
SNTKVDKKVEPK
3D structure
PDB5csz Gantenerumab: a novel human anti-Abeta antibody demonstrates sustained cerebral amyloid-Beta binding and elicits cell-mediated removal of human amyloid-Beta.
ChainA
Resolution1.8 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A Y32 A33 N52 A53 R57 Y59 Y60 G101 Y109 V110 Y31 A32 N51 A52 R56 Y58 Y59 G100 Y101 V102
External links