Structure of PDB 5cmb Chain A

Receptor sequence
>5cmbA (length=247) Species: 27923 (Mnemiopsis leidyi) [Search protein sequence]
LIGRHLRLGSVEEQPFMFFATEGCEGNDCWSGMVNDMVVKLSEDLGFTYE
YIQPDDRKFGALNKTTNEWNGMIRDLLDDKTDMIAIDLSTNSARKSAIDY
SFPFMDAGIKAVVKGEGTTLNQVLELLDQDKYKWGVIGSKHPETLLKTHR
DSRYSRLVDEGVELKDLNHAIETLRGGLFVFIDEGPVLAHNLISDCDVFS
VGEEFQSFEYAFGLPKDSPYKSLIDSHLLKFREEGFIDILWEKWSSG
3D structure
PDB5cmb Molecular lock regulates binding of glycine to a primitive NMDA receptor.
ChainA
Resolution1.34 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GLY A F63 D91 S93 R98 K144 H145 E188 F59 D87 S89 R94 K140 H141 E184 MOAD: Kd=28.3nM
BS02 MG A D110 E213 D106 E209
Gene Ontology
Molecular Function
GO:0015276 ligand-gated monoatomic ion channel activity
GO:0046872 metal ion binding
Biological Process
GO:0034220 monoatomic ion transmembrane transport
Cellular Component
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5cmb, PDBe:5cmb, PDBj:5cmb
PDBsum5cmb
PubMed27791085
UniProtA0A0R4I973

[Back to BioLiP]