Structure of PDB 5cm0 Chain A

Receptor sequence
>5cm0A (length=282) Species: 565033 (Geoglobus acetivorans) [Search protein sequence]
ELLVYMNGEFVPESQAKVSVFDHGFLYGDGVFEGIRAYNGKVFKLYEHID
RLYDCARVIDLKIPLSKEEFAEAILETLRRNNLRDAYIRPIVTRGAGDLG
LDPRKCPSPNVIIITKPWEKGLKAITVAIRRNAIDSLPPNIKSLNYLNNI
LAKIEANAKGGDEAIFLDHNGYISEGSGDNIFIVKNGTITTPPTLNNLKG
ITRQVVIELINELEIPFREANIGLFDLYSADEIFVTGTAAEIAPVTYIDG
RTVGNGKPGKVTKMLMEKFRERTENEGVEIYR
3D structure
PDB5cm0 Thermostable Branched-Chain Amino Acid Transaminases From the Archaea Geoglobus acetivorans and Archaeoglobus fulgidus : Biochemical and Structural Characterization.
ChainA
Resolution1.9 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) F34 G36 K152 E185 L208
Catalytic site (residue number reindexed from 1) F32 G34 K142 E175 L198
Enzyme Commision number 2.6.1.42: branched-chain-amino-acid transaminase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PLP A R53 K152 Y156 E185 G188 D189 L208 I211 T212 T248 R51 K142 Y146 E175 G178 D179 L198 I201 T202 T238
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004084 branched-chain-amino-acid transaminase activity
GO:0008483 transaminase activity
GO:0052654 L-leucine-2-oxoglutarate transaminase activity
GO:0052655 L-valine-2-oxoglutarate transaminase activity
GO:0052656 L-isoleucine-2-oxoglutarate transaminase activity
Biological Process
GO:0008652 amino acid biosynthetic process
GO:0009081 branched-chain amino acid metabolic process
GO:0009082 branched-chain amino acid biosynthetic process
GO:0009097 isoleucine biosynthetic process
GO:0009098 L-leucine biosynthetic process
GO:0009099 L-valine biosynthetic process
GO:0019752 carboxylic acid metabolic process
GO:0046394 carboxylic acid biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:5cm0, PDBe:5cm0, PDBj:5cm0
PDBsum5cm0
PubMed30733943
UniProtA0A0A7GJ30

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