Structure of PDB 5cks Chain A

Receptor sequence
>5cksA (length=339) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
NDDLRIKEIKELLPPVALLEKFPATENAANTVAHARKAIHKILKGNDDRL
LVVIGPCSIHDPVAAKEYATRLLALREELKDELEIVMRVYFEKPRTGWKG
LINDPHMDNSFQINDGLRIARKLLLDINDSGLPAAGEFLDMITPQYLADL
MSWGAIGARTTESQVHRELASGLSCPVGFKNGTDGTIKVAIDAINAAGAP
HCFLSVTKWGHSAIVNTSGNGDCHIILRGGKEPNYSAKHVAEVKEGLNKA
GLPAQVMIDFSHANSSKQFKKQMDVCADVCQQIAGGEKAIIGVMVESHLV
EGNQSLLAYGKSITDACIGWEDTDALLRQLANAVKARRG
3D structure
PDB5cks Potent Inhibition of 3-Deoxy-d-arabinoheptulosonate-7-phosphate (DAHP) Synthase by DAHP Oxime, a Phosphate Group Mimic.
ChainA
Resolution2.1181 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.5.1.54: 3-deoxy-7-phosphoheptulonate synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GAL A E96 N109 D146 T149 E92 N103 D140 T143
Gene Ontology
Molecular Function
GO:0003849 3-deoxy-7-phosphoheptulonate synthase activity
GO:0016740 transferase activity
GO:0042802 identical protein binding
Biological Process
GO:0008652 amino acid biosynthetic process
GO:0009058 biosynthetic process
GO:0009073 aromatic amino acid family biosynthetic process
GO:0009423 chorismate biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:5cks, PDBe:5cks, PDBj:5cks
PDBsum5cks
PubMed27933795
UniProtP0AB91|AROG_ECOLI Phospho-2-dehydro-3-deoxyheptonate aldolase, Phe-sensitive (Gene Name=aroG)

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