Structure of PDB 5ch5 Chain A

Receptor sequence
>5ch5A (length=566) Species: 7375 (Lucilia cuprina) [Search protein sequence]
VSLMEKLKWKIKCIENKFLNYRLTTNETVVAETEYGKVKGVKRLTVYDDS
YYSFEGIPYAQPPVGELRFKAPQRPTPWAGVRDCCNHKDKSVQVDFITGK
VCGSEDCLYLSVYTNNLNPETKRPVLVYIHGGGFIIGENHRDMYGPDYFI
KKDVVLINIQYRLGALGFLSLNSEDLNVPGNAGLKDQVMALRWIKNNCAN
FGGNPDNITVFGESAGAASTHYMMLTEQTRGLFHRGILMSGNAICPWANT
QCQHRAFTLAKLAGYKGEDNDKDVLEFLMKAKPQDLIKLEEKVLTLEERT
NKVMFPFGPTVEPYQTADCVLPKHPREMVKTAWGNSIPTMMGNTSYEGLF
FTSILKQMPLLVKELETCVNFVPSELADAERTAPETLEMGAKIKKAHVTG
ETPTADNFMDLCSHFYFWFPMHRLLQLRFNHTSGTPVYLYRFDFDSEDLI
NPYRIMRSGRGVKGVSHTDELTYFFWNQLAKRMPKESREYKTIERMTGIW
TQFATTGNPYSNEIEGMENVSWDPIEKSDEVYKCLNISDELKMIDVPEMG
KIKQWESMFEKHRDLF
3D structure
PDB5ch5 Mapping the Accessible Conformational Landscape of an Insect Carboxylesterase Using Conformational Ensemble Analysis and Kinetic Crystallography.
ChainA
Resolution1.53 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) G136 G137 G168 S218 A219 F309 F311 E351 H471
Catalytic site (residue number reindexed from 1) G132 G133 G164 S214 A215 F305 F307 E347 H467
Enzyme Commision number 3.1.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 DPF A G136 G137 S218 A219 W251 M308 Y457 H471 G132 G133 S214 A215 W247 M304 Y453 H467
Gene Ontology
Molecular Function
GO:0017171 serine hydrolase activity
GO:0052689 carboxylic ester hydrolase activity

View graph for
Molecular Function
External links
PDB RCSB:5ch5, PDBe:5ch5, PDBj:5ch5
PDBsum5ch5
PubMed27210287
UniProtQ25252

[Back to BioLiP]