Structure of PDB 5cgv Chain A

Receptor sequence
>5cgvA (length=178) Species: 641501 (Influenza A virus (A/California/04/2009(H1N1))) [Search protein sequence]
MEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSD
GGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIE
IGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRA
RIKTRLFTIRQEMASRSLWDSFRQSERA
3D structure
PDB5cgv Identification and characterization of influenza variants resistant to a viral endonuclease inhibitor.
ChainA
Resolution2.17 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN A H41 D108 E119 I120 H41 D89 E100 I101
BS02 MN A E80 P107 D108 E61 P88 D89
BS03 0N8 A Y24 I38 H41 E80 D108 E119 K134 K137 Y24 I38 H41 E61 D89 E100 K115 K118 PDBbind-CN: -logKd/Ki=6.47,Ki=0.34uM
Gene Ontology
Biological Process
GO:0039694 viral RNA genome replication

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:5cgv, PDBe:5cgv, PDBj:5cgv
PDBsum5cgv
PubMed26976575
UniProtC3W5S0

[Back to BioLiP]