Structure of PDB 5cfc Chain A

Receptor sequence
>5cfcA (length=252) Species: 434309 (Saffold virus) [Search protein sequence]
GVDNAEKGKVSDDNASTDFVAEPVKLPENQTRVSFFYDRSTLSSVLQSTS
DVSSKFTPSTAKNLQNSILLTPLPSDIVNNSVLPEQERWISFASPTTQKP
PYKTKQDWNFIMFSPFTYYKCDLEVTLSKNDRETISSVVRYVPCGAPSDL
SDQTMPQTPSLADTRDPHMWVVGQGTTNQISFVIPYTSPLSVLPSVWFNG
FSNFDNSSRFGVAPNADFGRLLLQGQGTFSVHYRYKKMRVFCPRPTVFIP
WP
3D structure
PDB5cfc Structure and Genome Release Mechanism of the Human Cardiovirus Saffold Virus 3.
ChainA
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.22.28: picornain 3C.
3.6.4.13: RNA helicase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A R32 F35 D38 D128 R242 K245 R32 F35 D38 D122 R234 K237
External links
PDB RCSB:5cfc, PDBe:5cfc, PDBj:5cfc
PDBsum5cfc
PubMed27279624
UniProtC0MHL9|POLG_SAFV Genome polyprotein

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