Structure of PDB 5cee Chain A

Receptor sequence
>5ceeA (length=387) Species: 322098 (Aster yellows witches'-broom phytoplasma AYWB) [Search protein sequence]
IKEKALEMHEKNKGKVGVVSKVKVQNLDDLSLVYTPGVAEPCLKIKENPS
DVYRYTMKGNMVGVITNGTAVLGLGNIGPKASLPVMEGKAILFKELAGID
SFPICIDSTDSQEIVNIVSKISTVFGAINLEDIKSPQCIEIEDALKAKLD
IPVFHDDQHGTAIVVAAGILNALKVVKKSIEDVQVVINGAGSAGMAIAKM
LLLLKVNNVVLVDKTGTLYKGVANLNEPQKKLVEVTNKYQEKGTLKEVLK
GKDIFIGVSAPGIVTAEMVATMAKDAIVFALANPVPEIMPDEAKKGGARI
VATGRSDFPNQVNNCLAFPGVFRGTLDAKATQITEEMKKAATYALKNIIK
EQDLNENNILPTSFNKEVVKQIALAVCKVAKETGVVR
3D structure
PDB5cee The crystal structure of the malic enzyme from Candidatus Phytoplasma reveals the minimal structural determinants for a malic enzyme.
ChainA
Resolution2.498 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) Y36 A72 K91 E133 D134 D158 D159 N285
Catalytic site (residue number reindexed from 1) Y34 A70 K89 E131 D132 D156 D157 N283
Enzyme Commision number 1.1.1.38: malate dehydrogenase (oxaloacetate-decarboxylating).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAD A T163 N190 G191 G193 A195 D215 K216 V260 S261 I265 L283 N285 V314 N316 T161 N188 G189 G191 A193 D213 K214 V258 S259 I263 L281 N283 V312 N314
BS02 MG A E133 D134 D159 E131 D132 D157
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003824 catalytic activity
GO:0004470 malic enzyme activity
GO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity
GO:0008948 oxaloacetate decarboxylase activity
GO:0016491 oxidoreductase activity
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0046872 metal ion binding
GO:0051287 NAD binding

View graph for
Molecular Function
External links
PDB RCSB:5cee, PDBe:5cee, PDBj:5cee
PDBsum5cee
PubMed29652260
UniProtQ2NK75

[Back to BioLiP]