Structure of PDB 5cd4 Chain A

Receptor sequence
>5cd4A (length=199) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
MYLSKVIIARAWSRDLYQLHQGLWHLFPNRPDAARDFLFHVEKRNTPEGC
HVLLQSAQMPVSTAVATVIKTKQVEFQLQVGVPLYFRLRANPIKTILDNQ
KRLDSKGNIKRCRVPLIKEAEQIAWLQRKLGNAARVEDVHPISERPQYFS
GDGKSGKIQTVCFEGVLTINDAPALIDLVQQGIGPAKSMGCGLLSLAPL
3D structure
PDB5cd4 Mechanism of CRISPR-RNA guided recognition of DNA targets in Escherichia coli.
ChainA
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A Y17 A34 R35 N91 K94 T95 I96 D98 N99 R102 S105 K106 K110 R113 V114 P115 I117 R128 K129 F149 K154 G156 K157 Q159 K187 S188 Y17 A34 R35 N91 K94 T95 I96 D98 N99 R102 S105 K106 K110 R113 V114 P115 I117 R128 K129 F149 K154 G156 K157 Q159 K187 S188
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0004519 endonuclease activity
GO:0004521 RNA endonuclease activity
GO:0005515 protein binding
Biological Process
GO:0006396 RNA processing
GO:0051607 defense response to virus
GO:0099048 CRISPR-cas system
Cellular Component
GO:0032991 protein-containing complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5cd4, PDBe:5cd4, PDBj:5cd4
PDBsum5cd4
PubMed26243775
UniProtQ46897|CAS6_ECOLI CRISPR system Cascade subunit CasE (Gene Name=casE)

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