Structure of PDB 5c85 Chain A

Receptor sequence
>5c85A (length=112) Species: 9606 (Homo sapiens) [Search protein sequence]
MQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLSEVPDYLDHIKKPMDFFT
MKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVRLREQGGA
VLRQARRQAEKM
3D structure
PDB5c85 Twenty Crystal Structures of Bromodomain and PHD Finger Containing Protein 1 (BRPF1)/Ligand Complexes Reveal Conserved Binding Motifs and Rare Interactions.
ChainA
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 4YO A I652 V657 P658 F714 I25 V30 P31 F87 MOAD: Kd=105uM
PDBbind-CN: -logKd/Ki=3.98,Kd=105uM
BindingDB: Kd=105000nM
External links
PDB RCSB:5c85, PDBe:5c85, PDBj:5c85
PDBsum5c85
PubMed27167503
UniProtP55201|BRPF1_HUMAN Peregrin (Gene Name=BRPF1)

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