Structure of PDB 5c7n Chain A

Receptor sequence
>5c7nA (length=112) Species: 9606 (Homo sapiens) [Search protein sequence]
MQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLSEVPDYLDHIKKPMDFFT
MKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVRLREQGGA
VLRQARRQAEKM
3D structure
PDB5c7n Twenty Crystal Structures of Bromodomain and PHD Finger Containing Protein 1 (BRPF1)/Ligand Complexes Reveal Conserved Binding Motifs and Rare Interactions.
ChainA
Resolution1.75 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BMF A V657 P658 V662 Y707 N708 F714 V30 P31 V35 Y80 N81 F87 MOAD: Kd=0.27uM
PDBbind-CN: -logKd/Ki=6.57,Kd=0.27uM
BindingDB: IC50=141nM
External links
PDB RCSB:5c7n, PDBe:5c7n, PDBj:5c7n
PDBsum5c7n
PubMed27167503
UniProtP55201|BRPF1_HUMAN Peregrin (Gene Name=BRPF1)

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