Structure of PDB 5c7k Chain A

Receptor sequence

>5c7kA (length=230) Species: 9606 (Homo sapiens) [Search protein sequence]

PQLQESGPTLVEASETLSLTCAVSGDSTAACNSFWGWVRQPPGKGLEWVG
SLSHCASYWNRGWTYHNPSLKSRLTLALDTPKNLVFLKLNSVTAADTATY
YCARFGGEVLRYTDWPKPAWVDLWGRGTLVTVSSASTKGPSVFPLAPSSG
GTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVT
VPSSSLGTQTYICNVNHKPSNTKVDKRVEP

3D structure

PDB

5c7k Complete epitopes for vaccine design derived from a crystal structure of the broadly neutralizing antibodies PGT128 and 8ANC195 in complex with an HIV-1 Env trimer.

Chain

Resolution

4.6019 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	MAN	A	W56 T57	W63 T64
BS02	MAN	A	Y58 H59 K64	Y65 H66 K71

External links

PDB	RCSB:5c7k, PDBe:5c7k, PDBj:5c7k
PDBsum	5c7k
PubMed	26457433
UniProt	S6B291

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