Structure of PDB 5c6p Chain A

Receptor sequence
>5c6pA (length=459) Species: 242231 (Neisseria gonorrhoeae FA 1090) [Search protein sequence]
LDRFSFSVFLKEIRLLTALALPMLLAQVAQVGIGFVDTVMAGGAGKEDLA
AVALGSSAFATVYITFMGIMAALNPMIAQLYGAGKTGEAGETGRQGIWFG
LILGIFGMILMWAAITPFRNWLTLSDYVEGTMAQYMLFTSLAMPAAMVHR
ALHAYASSLNRPRLIMLVSFAAFVLNVPLNYIFVYGKFGMPALGGAGCGV
ATMAVFWFSALALWIYIAKEKFFRPFGLTAKFGKPDWAVFKQIWKIGAPI
GLSYFLEASAFSFIVFLIAPFGEDYVAAQQVGISLSGILYMIPQSVGSAG
TVRIGFSLGRREFSRARYISGVSLVSGWVLAVITVLSLVLFRSPLASMYN
DDPAVLSIASTVLLFAGLFQPADFTQCIASYALRGYKVTKVPMFIHAAAF
WGCGLLPGYLLAYRFDMGIYGFWTALIASLTIAAVALVWCLEKYSMELVK
SHKAVSSGL
3D structure
PDB5c6p Structural basis for the blockade of MATE multidrug efflux pumps.
ChainA
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 4YH A A57 S61 Q284 S288 D356 P357 A53 S57 Q280 S284 D352 P353 PDBbind-CN: -logKd/Ki=3.70,Ki>200uM
Gene Ontology
Molecular Function
GO:0015297 antiporter activity
GO:0042910 xenobiotic transmembrane transporter activity
Biological Process
GO:0006811 monoatomic ion transport
GO:0042908 xenobiotic transport
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5c6p, PDBe:5c6p, PDBj:5c6p
PDBsum5c6p
PubMed26246409
UniProtQ5F9J8

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