Structure of PDB 5c6d Chain A

Receptor sequence
>5c6dA (length=311) Species: 9606 (Homo sapiens) [Search protein sequence]
AHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLS
QTMGFPQDQIRLWPMQARSNGTKRPAMLADGNKTMIELSDNENPWTIFLE
TVDPTLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVM
CDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQK
DDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYF
QVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKP
RQPKKLYYQQL
3D structure
PDB5c6d An Allosteric Interaction Links USP7 to Deubiquitination and Chromatin Targeting of UHRF1.
ChainA
Resolution2.292 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.19.12: ubiquitinyl hydrolase 1.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Q626 A627 R628 S629 N630 E736 E744 D758 E759 M761 D764 Q66 A67 R68 S69 N70 E166 E174 D188 E189 M191 D194
External links
PDB RCSB:5c6d, PDBe:5c6d, PDBj:5c6d
PDBsum5c6d
PubMed26299963
UniProtQ93009|UBP7_HUMAN Ubiquitin carboxyl-terminal hydrolase 7 (Gene Name=USP7)

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