Structure of PDB 5c3f Chain A

Receptor sequence
>5c3fA (length=151) Species: 9606 (Homo sapiens) [Search protein sequence]
SELYRQSLEIISRYLREQATGAKDTKPMGRSGATSRKALETLRRVGDGVQ
RNHETAFQGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISFG
AFVAKHLKTINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFFHV
E
3D structure
PDB5c3f Hydrocarbon constrained peptides - understanding preorganisation and binding affinity.
ChainA
Resolution1.43 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A V220 H224 M231 L235 R248 V249 H252 V253 N260 G262 R263 V265 T266 F318 F319 V49 H53 M60 L64 R77 V78 H81 V82 N89 G91 R92 V94 T95 F147 F148
Gene Ontology
Biological Process
GO:0042981 regulation of apoptotic process

View graph for
Biological Process
External links
PDB RCSB:5c3f, PDBe:5c3f, PDBj:5c3f
PDBsum5c3f
PubMed28970875
UniProtQ07820|MCL1_HUMAN Induced myeloid leukemia cell differentiation protein Mcl-1 (Gene Name=MCL1)

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