Structure of PDB 5c1m Chain A

Receptor sequence
>5c1mA (length=296) Species: 10090 (Mus musculus) [Search protein sequence]
GSHSLCPQTGSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKT
ATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGNILCKIVISIDYYNM
FTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIVNVCNWILSSAIGLP
VMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVC
YGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVI
IKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCF
3D structure
PDB5c1m Structural insights into mu-opioid receptor activation.
ChainA
Resolution2.07 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CLR A P295 Y299 I308 P244 Y248 I257
BS02 VF1 A H54 D147 M151 Y326 H3 D96 M100 Y275
Gene Ontology
Molecular Function
GO:0004930 G protein-coupled receptor activity
GO:0004979 beta-endorphin receptor activity
GO:0004985 G protein-coupled opioid receptor activity
Biological Process
GO:0007186 G protein-coupled receptor signaling pathway
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5c1m, PDBe:5c1m, PDBj:5c1m
PDBsum5c1m
PubMed26245379
UniProtP42866|OPRM_MOUSE Mu-type opioid receptor (Gene Name=Oprm1)

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