Structure of PDB 5c11 Chain A

Receptor sequence
>5c11A (length=52) Species: 9606 (Homo sapiens) [Search protein sequence]
SVCAAQNCQRPCKDKVDWVQCDGGCDEWFHQVCVGVSPEMAENEDYICIN
CA
3D structure
PDB5c11 Crystal Structure of Jarid1a PHD finger bound to histone H3C4me3 peptide
ChainA
Resolution2.803 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.14.11.67: [histone H3]-trimethyl-L-lysine(4) demethylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A K15 V16 D17 W18 V19 Q20 D22 W28 A41 E44 K15 V16 D17 W18 V19 Q20 D22 W28 A41 E44
BS02 ZN A C3 C8 H30 C33 C3 C8 H30 C33
BS03 ZN A C21 C25 C48 C51 C21 C25 C48 C51
External links
PDB RCSB:5c11, PDBe:5c11, PDBj:5c11
PDBsum5c11
PubMed
UniProtP29375|KDM5A_HUMAN Lysine-specific demethylase 5A (Gene Name=KDM5A)

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