Structure of PDB 5c0e Chain A

Receptor sequence
>5c0eA (length=277) Species: 9606 (Homo sapiens) [Search protein sequence]
MGSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRA
PWIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMY
GCDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEA
AHVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEA
TLRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVV
PSGQEQRYTCHVQHEGLPKPLTLRWEP
3D structure
PDB5c0e Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
ChainA
Resolution1.491 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Y7 M45 E63 K66 V67 A69 H70 T73 D77 Y84 R97 Y99 H114 T143 K146 W147 V152 Y159 T163 W167 Y171 Y8 M46 E64 K67 V68 A70 H71 T74 D78 Y85 R98 Y100 H115 T144 K147 W148 V153 Y160 T164 W168 Y172
External links
PDB RCSB:5c0e, PDBe:5c0e, PDBj:5c0e
PDBsum5c0e
PubMed27183389
UniProtP04439|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)

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