Structure of PDB 5c0c Chain A

Receptor sequence
>5c0cA (length=276) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGQEQRYTCHVQHEGLPKPLTLRWEP
3D structure
PDB5c0c Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
ChainA
Resolution1.974 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Y7 M45 E63 K66 V67 H70 D77 R97 Y99 H114 T143 K146 W147 V152 L156 Y159 W167 Y171 Y7 M45 E63 K66 V67 H70 D77 R97 Y99 H114 T143 K146 W147 V152 L156 Y159 W167 Y171
External links
PDB RCSB:5c0c, PDBe:5c0c, PDBj:5c0c
PDBsum5c0c
PubMed27183389
UniProtP04439|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)

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