Structure of PDB 5c07 Chain A

Receptor sequence
>5c07A (length=276) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGQEQRYTCHVQHEGLPKPLTLRWEP
3D structure
PDB5c07 Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
ChainA
Resolution2.11 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A Y7 M45 E63 K66 V67 H70 D77 Y84 R97 Y99 H114 T143 W147 Q155 Y159 T163 W167 Y171 Y7 M45 E63 K66 V67 H70 D77 Y84 R97 Y99 H114 T143 W147 Q155 Y159 T163 W167 Y171
External links
PDB RCSB:5c07, PDBe:5c07, PDBj:5c07
PDBsum5c07
PubMed27183389
UniProtP04439|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)

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