Structure of PDB 5bt5 Chain A

Receptor sequence
>5bt5A (length=110) Species: 9606 (Homo sapiens) [Search protein sequence]
LSEQLKHCNGILKELLSKKHAAYAWPFYKPVDASALGLHDYHDIIKHPMD
LSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDV
FEFRYAKMPD
3D structure
PDB5bt5 Crystal structure of BRD2 second bromodomain in complex with a 3,5-dimethylisoxazol ligand
ChainA
Resolution1.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 2LO A W370 P371 F372 L381 V435 W25 P26 F27 L36 V90
External links
PDB RCSB:5bt5, PDBe:5bt5, PDBj:5bt5
PDBsum5bt5
PubMed
UniProtP25440|BRD2_HUMAN Bromodomain-containing protein 2 (Gene Name=BRD2)

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