Structure of PDB 5brm Chain A

Receptor sequence
>5brmA (length=154) Species: 9606 (Homo sapiens) [Search protein sequence]
DLNEWIAVNTVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWADGT
NIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPFPKNFMSVAKTILKRLFR
VYAHIYHQHFDSVMQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQEL
IEKL
3D structure
PDB5brm Structural basis for Mob1-dependent activation of the core Mst-Lats kinase cascade in Hippo signaling.
ChainA
Resolution2.651 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A R92 E94 Y95 H96 K153 R154 R157 Y163 F167 M171 N180 E200 E206 L207 R41 E43 Y44 H45 K96 R97 R100 Y106 F110 M114 N123 E143 E149 L150
BS02 peptide A V62 N66 N69 Y72 D116 Q123 L126 D127 V11 N15 N18 Y21 D65 Q72 L75 D76
BS03 ZN A C79 C84 H161 H166 C28 C33 H104 H109
External links
PDB RCSB:5brm, PDBe:5brm, PDBj:5brm
PDBsum5brm
PubMed26108669
UniProtQ9H8S9|MOB1A_HUMAN MOB kinase activator 1A (Gene Name=MOB1A)

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