Structure of PDB 5bo7 Chain A

Receptor sequence
>5bo7A (length=290) Species: 9606 (Homo sapiens) [Search protein sequence]
KWKFNRTAFLHQRQEILQHVDVIKNFSLTKNSVRIGQLMHYDYSSHKYVF
SISNNFRSLLPDVSPIMNKHYNICAVVGNSGILTGSQCGQEIDKSDFVFR
CNFAPTEAFQRDVGRKTNLTTFNPSILEKYYNNLLTIQDRNNFFLSLKKL
DGAILWIPAFFFHTSATVTRTLVDFFVEHRGQLKVQLAWPGNIMQHVNRY
WKNKHLSPKRLSTGILMYTLASAICEEIHLYGFWPFGFDPNTREDLPYHY
YDKKGTKFTTKESHQLPAEFQLLYRMHGEGLTKLTLSHCA
3D structure
PDB5bo7 Structure of human ST8SiaIII sialyltransferase provides insight into cell-surface polysialylation.
ChainA
Resolution1.85 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) R298 H354
Catalytic site (residue number reindexed from 1) R210 H264
Enzyme Commision number 2.4.3.-
2.4.3.8: alpha-N-acetylneuraminate alpha-2,8-sialyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CTP A N167 S168 C189 N190 S300 T301 G302 F321 W322 P323 Y336 H337 H354 N79 S80 C101 N102 S212 T213 G214 F233 W234 P235 Y248 H249 H264
Gene Ontology
Molecular Function
GO:0008373 sialyltransferase activity
Biological Process
GO:0006486 protein glycosylation

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Molecular Function
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Biological Process
External links
PDB RCSB:5bo7, PDBe:5bo7, PDBj:5bo7
PDBsum5bo7
PubMed26192331
UniProtO43173|SIA8C_HUMAN Alpha-N-acetylneuraminate alpha-2,8-sialyltransferase ST8SIA3 (Gene Name=ST8SIA3)

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