Structure of PDB 5b89 Chain A

Receptor sequence
>5b89A (length=400) Species: 523850 (Thermococcus onnurineus NA1) [Search protein sequence]
MASMRIPEDVRKDIPLTNEVIYFDNTATSLTPKPVVEAMDEYYLKYRANV
HRGVHRLSQMATHKYEESRKIVADFIGAKFEEIVFTKNTSESLNLVALGL
GHIFKRGDKIVTTPYEHHSDLLPWQRLATKLGLKLEFIEGDDEGNLDLSD
AEKKIKGAKLVAVQHVSNALGVIHEVEELGKIAKDEGAIFVVDAAQSAGH
MEVNVKKLHADFLAFSGHKGPMGPTGIGVLYIREEFFDTFEPPLIGGGTI
EDVSLDGYKLTEPPERFEAGTPNIGGAIGLAAGIRYIERIGLGRIERQEH
KLVKRTTEGLDELEVPWYGPRNLKKHAGVVSFNVPGLHPHDVAAILDDHS
IMVRSGHHCALPVMKKLGINGTVRASFHVYNSLEEVETFLGVMEELVKGL
3D structure
PDB5b89 Catalytic Intermediate Crystal Structures of Cysteine Desulfurase from the ArchaeonThermococcus onnurineus NA1.
ChainA
Resolution1.5 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H114 D190 A192 Q193 K216 R351 C356
Catalytic site (residue number reindexed from 1) H117 D193 A195 Q196 K219 R354 C359
Enzyme Commision number 2.8.1.7: cysteine desulfurase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ALA A A24 K216 R371 A27 K219 R374
BS02 PLP A N85 T86 S87 H114 D190 A192 Q193 S213 K216 N88 T89 S90 H117 D193 A195 Q196 S216 K219
BS03 PLP A G267 T268 G270 T271
Gene Ontology
Molecular Function
GO:0030170 pyridoxal phosphate binding
GO:0031071 cysteine desulfurase activity
Biological Process
GO:0006534 cysteine metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:5b89, PDBe:5b89, PDBj:5b89
PDBsum5b89
PubMed28536498
UniProtB6YT87

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