Structure of PDB 5b7n Chain A

Receptor sequence
>5b7nA (length=248) Species: 380703 (Aeromonas hydrophila subsp. hydrophila ATCC 7966) [Search protein sequence]
SAPILIQGAMDVEVETLVAALKDKQELTVGSWTYWQGTLSGYPVVVSRTE
VGLANAAAATTLAMERFQPRLVINQGTAGGHDPALHRGDIVIGTKSFNMG
AYRSDLTPAEQGVDPSKWHNFEVTMRLRDNGKLVEHSSFAGDPELVGRAL
GMADRYRHGRVVPGIIGTADEWNRQVARINWLHQTYQTAAEEMETSSAAL
VAEAYKVPFVGIRVLSNTDLHGEEFDPQTAIHCQQFVIDYAKALINGF
3D structure
PDB5b7n Structural and Functional Analyses of Periplasmic 5'-Methylthioadenosine/S-Adenosylhomocysteine Nucleosidase from Aeromonas hydrophila.
ChainA
Resolution1.399 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) A90
Catalytic site (residue number reindexed from 1) A63
Enzyme Commision number 3.2.2.16: methylthioadenosine nucleosidase.
3.2.2.9: adenosylhomocysteine nucleosidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SAH A M37 V78 T104 A105 G106 W199 E218 E219 M220 E221 N244 M10 V51 T77 A78 G79 W172 E191 E192 M193 E194 N217
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0008782 adenosylhomocysteine nucleosidase activity
GO:0008930 methylthioadenosine nucleosidase activity
GO:0016798 hydrolase activity, acting on glycosyl bonds
Biological Process
GO:0009116 nucleoside metabolic process
GO:0019284 L-methionine salvage from S-adenosylmethionine
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5b7n, PDBe:5b7n, PDBj:5b7n
PDBsum5b7n
PubMed28862845
UniProtA0KGU9

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