Structure of PDB 5b77 Chain A

Receptor sequence

>5b77A (length=116) Species: 9606 (Homo sapiens) [Search protein sequence]

EKDKPVAEPIPICSFCLGTKEQNREKKPEELISCADCGNSGHPSCLKFSP
ELTVRVKALRWQCIECKTCSSCRDQGKNADNMLFCDSCDRGFHMECCDPP
LTRMPKGMWICQICRP

3D structure

PDB

5b77 Selective recognition of histone crotonylation by double PHD fingers of MOZ and DPF2

Chain

Resolution

1.551 Å

3D
structure

Enzymatic activity

Enzyme Commision number

2.3.1.48: histone acetyltransferase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	peptide	A	I208 S210 F211 L213 S236 K243 I260 E261 A275 D276 M278 L279 F280 C281 D282 D285 M300 G303	I12 S14 F15 L17 S40 K47 I64 E65 A79 D80 M82 L83 F84 C85 D86 D89 M104 G107
BS02	ZN	A	C281 C284 C307 C310	C85 C88 C111 C114
BS03	ZN	A	C265 C268 H289 C292	C69 C72 H93 C96
BS04	ZN	A	C209 C212 H238 C241	C13 C16 H42 C45
BS05	ZN	A	C230 C233 C259 C262	C34 C37 C63 C66

External links

PDB	RCSB:5b77, PDBe:5b77, PDBj:5b77
PDBsum	5b77
PubMed	27775714
UniProt	Q92794\|KAT6A_HUMAN Histone acetyltransferase KAT6A (Gene Name=KAT6A)