Structure of PDB 5b6b Chain A

Receptor sequence
>5b6bA (length=182) Species: 10090 (Mus musculus) [Search protein sequence]
SHQYELLKHAENLRMAVMLPEGEDLNEWVAVNTVDFFNQINMLYGTITDF
CTEESCPVMSAGPKYEYHWADGTKPIKCSAPKYIDYLMTWVQDQLDDETL
FPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDPVIQLQEEAHLNT
SFKHFIFFVQEFNLIDRRELAPLQELIEKLTS
3D structure
PDB5b6b Structural basis for autoinhibition and its relief of MOB1 in the Hippo pathway
ChainA
Resolution3.536 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C84 H161 H166 C56 H130 H135
Gene Ontology
Molecular Function
GO:0019209 kinase activator activity
GO:0019900 kinase binding
GO:0046872 metal ion binding
Biological Process
GO:0031952 regulation of protein autophosphorylation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5b6b, PDBe:5b6b, PDBj:5b6b
PDBsum5b6b
PubMed27335147
UniProtQ8BPB0|MOB1B_MOUSE MOB kinase activator 1B (Gene Name=Mob1b)

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