Structure of PDB 5b5u Chain A

Receptor sequence
>5b5uA (length=175) Species: 186497 (Pyrococcus furiosus DSM 3638) [Search protein sequence]
MKILLIGMGGTIASVKGENGYEASLSVKEVLDIAGIKDCEDCDFLDLKNV
DSTLIQPEDWVDLAETLYKNVKKYDGIIVTHGTDTLAYTSSMISFMLRNP
PIPIVFTGSMIPATEENSDAPLNLQTAIKFATSGIRGVYVAFNGKVMLGV
RTSKVRTMSRDAFESINYPIIAELR
3D structure
PDB5b5u Heat induces end to end repetitive association in P. furiosus L-asparaginase which enables its thermophilic property.
ChainA
Resolution2.61 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) T11 Y21 T83 D84 K154
Catalytic site (residue number reindexed from 1) T11 Y21 T83 D84 K154
Enzyme Commision number 3.5.1.1: asparaginase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A I171 A172 E173 L174 R175 I171 A172 E173 L174 R175
BS02 peptide A D43 F44 D43 F44
BS03 ASP A T11 D51 S52 G82 T83 D84 S109 M110 T11 D51 S52 G82 T83 D84 S109 M110
External links
PDB RCSB:5b5u, PDBe:5b5u, PDBj:5b5u
PDBsum5b5u
PubMed33303914
UniProtQ8TZE8|ASPG_PYRFU L-asparaginase (Gene Name=PF2047)

[Back to BioLiP]