Structure of PDB 5ayk Chain A

Receptor sequence
>5aykA (length=744) Species: 10090 (Mus musculus) [Search protein sequence]
QNFYSLLGVSKTASSREIRQAFKKLALKLHPDKNPNNPNAHGDFLKINRA
YEVLKDEDLRKKYDKYGEKGLEDNQGGQYESWSYYRYDFGIYDDDPEIIT
LERREFDAAVNSGELWFVNFYSPGSSHSHDLAPTWREFAKEVDGLLRIGA
VNCGDDRMLCRMKGVNSYPSLFIFRSGMAAVKYNGDRSKESLVAFAMQHV
RSTVTELSTGNFVNAIETAFAAGVGWLITFCSKGEDCLTSQTRLRLSGML
DGLVNVGWVDCDAQDSLCKSLDSTTAYFPPGATLNDREKSSVLFLNSLDA
KEIYMEIIHNLPDFELLSANQLEDRLAHHRWLVFFHFGKNNDPELKKLKT
LLKNEHIQVVRFDCSSAPGICSDLYVFQPSLAVFKGQGTKEYEIHHGKKI
LYDILAFAKESVNSHVTTLGPQNFPASDKEPWLVDFFAPWSPPSRALLPE
LRKASTLLYGQLKVGTLDCTIHEGLCNMYNIQAYPTTVVFNQSSIHEYEG
HHSAEQILEFIEDLRNPSVVSLTPSTFNELVKQRKHDEVWMVDFYSPWSH
PSQVLMPEWKRMARTLTGLINVGSVDCQQYHSFCTQENVQRYPEIRFYPQ
KSSKAYQYHSYNGWNRDAYSLRSWGLGFLPQASIDLTPQTFNEKVLQGKT
HWVVDFYAPWSGPSQNFAPEFELLARMIKGKVRAGKVDCQAYPQTCQKAG
IKAYPSVKLYQYERAKKSIWEEQINSRDAKTIAALIYGKLETLQ
3D structure
PDB5ayk Highly dynamic nature of ERdj5 is essential for enhancement of the ER associated degradation
ChainA
Resolution2.25 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H345 N346 L347 P348
Catalytic site (residue number reindexed from 1) H309 N310 L311 P312
Enzyme Commision number 1.8.4.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 1PS A Y112 E113 S114 Y79 E80 S81
Gene Ontology
Molecular Function
GO:0015036 disulfide oxidoreductase activity
Biological Process
GO:0034975 protein folding in endoplasmic reticulum
Cellular Component
GO:0005783 endoplasmic reticulum

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5ayk, PDBe:5ayk, PDBj:5ayk
PDBsum5ayk
PubMed
UniProtQ9DC23|DJC10_MOUSE DnaJ homolog subfamily C member 10 (Gene Name=Dnajc10)

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