Structure of PDB 5awu Chain A

Receptor sequence
>5awuA (length=265) Species: 9606 (Homo sapiens) [Search protein sequence]
TLPVAAAFTETVNAYFKGADPSKCIVKITGEMVLSFPAGITRHFANNPSP
AALTFRVINFSRLEHVLPNPQLLCCDANTKEFWVNMPNLMTHLKKVSEQK
PQATYYNVDMLKYQVSAQGIQSTPLNLAVNWRCEPSSTDLRIDYKYNTDA
MTTAVALNNVQFLVPIDGGVTKLQAVLPPAVWNAEQQRILWKIPDISQKS
ENGGVGSLLARFQLSEGPSKPSPLVVQFTSEGSTLSGCDIELVGAGYRFS
LIKKRFAAGKYLADN
3D structure
PDB5awu Structural basis for the recognition of two consecutive mutually interacting DPF motifs by the SGIP1 mu homology domain.
ChainA
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A P561 V562 A564 A565 S593 P595 Y668 N670 S813 R818 P3 V4 A6 A7 S35 P37 Y105 N107 S250 R255
BS02 ZN A E589 D672 E31 D109
Gene Ontology
Biological Process
GO:0072583 clathrin-dependent endocytosis

View graph for
Biological Process
External links
PDB RCSB:5awu, PDBe:5awu, PDBj:5awu
PDBsum5awu
PubMed26822536
UniProtQ9BQI5|SGIP1_HUMAN SH3-containing GRB2-like protein 3-interacting protein 1 (Gene Name=SGIP1)

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