Structure of PDB 5av8 Chain A

Receptor sequence
>5av8A (length=99) Species: 9606 (Homo sapiens) [Search protein sequence]
KPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQS
SAVMALQEACEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA
3D structure
PDB5av8 Intra- and inter-nucleosomal interactions of the histone H4 tail revealed with a human nucleosome core particle with genetically-incorporated H4 tetra-acetylation
ChainA
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A K37 Y41 R42 P43 T45 R63 R72 R83 F84 Q85 S86 R116 V117 T118 M120 K1 Y5 R6 P7 T9 R27 R36 R47 F48 Q49 S50 R80 V81 T82 M84
BS02 dna A H39 R40 Y41 P43 G44 V46 A47 R49 R63 K64 L65 R69 R83 H3 R4 Y5 P7 G8 V10 A11 R13 R27 K28 L29 R33 R47
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0045296 cadherin binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0006325 chromatin organization
GO:0006334 nucleosome assembly
GO:0010467 gene expression
GO:0032200 telomere organization
GO:0040029 epigenetic regulation of gene expression
Cellular Component
GO:0000786 nucleosome
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0016020 membrane
GO:0032991 protein-containing complex
GO:0070062 extracellular exosome

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Molecular Function
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Cellular Component
External links
PDB RCSB:5av8, PDBe:5av8, PDBj:5av8
PDBsum5av8
PubMed26607036
UniProtP68431|H31_HUMAN Histone H3.1 (Gene Name=H3C1)

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