Structure of PDB 5aul Chain A

Receptor sequence
>5aulA (length=109) Species: 9606 (Homo sapiens) [Search protein sequence]
GSEDLPHHDEKTWNVGSSNRNKAENLLRGKRDGTFLVRESSKQGCYACSV
VVDGEVKHCVINKTATGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLN
VTLAYPVYA
3D structure
PDB5aul Crystal Structures and Thermodynamic Analysis Reveal Distinct Mechanisms of CD28 Phosphopeptide Binding to the Src Homology 2 (SH2) Domains of Three Adaptor Proteins
ChainA
Resolution1.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A R631 R649 S651 S652 K653 H669 C670 F681 A682 H706 N707 L710 R20 R38 S40 S41 K42 H58 C59 F70 A71 H95 N96 L99
External links
PDB RCSB:5aul, PDBe:5aul, PDBj:5aul
PDBsum5aul
PubMed27927989
UniProtP27986|P85A_HUMAN Phosphatidylinositol 3-kinase regulatory subunit alpha (Gene Name=PIK3R1)

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