Structure of PDB 5ajk Chain A

Receptor sequence
>5ajkA (length=148) Species: 10255 (Variola virus) [Search protein sequence]
HNYVYPLPESTNILDYLSTERDHVMMAVQYYMSKQRLDDLYRQLPTKTRS
YIDIINMYCDKVNNDYNRDMNIMYDMASTESFTVYDINNEVNTILMDNKG
LGVRLATISFITELGKRCMNPVETIKMFTLLSHTICDDCFIDYITDIS
3D structure
PDB5ajk Variola Virus F1L is a Bcl-2-Like Protein that Unlike its Vaccinia Virus Counterpart Inhibits Apoptosis Independent of Bim.
ChainA
Resolution2.55 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A K114 D118 Y119 M126 M129 E133 E143 I147 G155 V156 K61 D65 Y66 M73 M76 E80 E90 I94 G102 V103
Gene Ontology
Biological Process
GO:0033668 symbiont-mediated suppression of host apoptosis
GO:0042981 regulation of apoptotic process

View graph for
Biological Process
External links
PDB RCSB:5ajk, PDBe:5ajk, PDBj:5ajk
PDBsum5ajk
PubMed25766319
UniProtQ85365|PG045_VARV Apoptosis regulator OPG045 (Gene Name=OPG045)

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