Structure of PDB 5ahm Chain A

Receptor sequence
>5ahmA (length=354) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence]
MLRISQEALTFDDVLLIPGYSEVLPKDVSLKTRLTRGIELNIPLVSAAMD
TVTEARLAIAMAQEGGIGIIHKNMGIEQQAAEVRKVKKHETAKAKTYPLA
SKDEQGRLRVGAAVGTGADTGERVAALVAAGVDVVVVDTAHGHSKGVIER
VRWVKQTFPDVQVIGGNIATAEAAKALAEAGADAVKVGIGPGSICTTRIV
AGVGVPQISAIANVAAALEGTGVPLIADGGIRFSGDLAKAMVAGAYCVMM
GSMFAGTEEAPGEIELFQGRSYKSYRGMGSLVPEGIEGRVPYKGALSAIV
HQLMGGLRAAMGYTGSADIQQMRTQPQFVRITGAGMAESHVHDVQITKEA
PNYR
3D structure
PDB5ahm Crystallographic Studies of Two Variants of Pseudomonas Aeruginosa Impdh with Impaired Allosteric Regulation
ChainA
Resolution1.74 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.1.1.205: IMP dehydrogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 IMP A M49 G301 S302 I303 C304 D337 M359 G360 S361 Y384 G386 M387 G388 E417 M49 G192 S193 I194 C195 D228 M250 G251 S252 Y275 G277 M278 G279 E284
BS02 PO4 A Q63 H89 A92 Y206 Q63 H89 A92 Y97
BS03 PO4 A D212 E213 R218 D103 E104 R109
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0003938 IMP dehydrogenase activity
GO:0016491 oxidoreductase activity
Biological Process
GO:0006164 purine nucleotide biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:5ahm, PDBe:5ahm, PDBj:5ahm
PDBsum5ahm
PubMed26327379
UniProtQ9HXM5

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