Structure of PDB 5afw Chain A

Receptor sequence
>5afwA (length=163) Species: 9606 (Homo sapiens) [Search protein sequence]
EFETIERFMDCRIGRKGATGATTTIYAVEADGDPNAGFEKNKEPGEIQYL
IKWKGWSHIHNTWETEETLKQQNVRGMKKLDNYKKKDQETKRWYNCQQEL
TDDLHKQYQIVERIIAHSNQKSAAGYPDYYCKWQGLPYSECSWEDGALIS
KKFQACIDEYFSR
3D structure
PDB5afw Assembly of Methylated Kdm1A and Chd1 Drives Androgen Receptor-Dependent Transcription and Translocation.
ChainA
Resolution1.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A A290 T293 Y295 W322 W325 D408 W423 E424 D425 L428 A21 T24 Y26 W53 W56 D128 W143 E144 D145 L148
External links
PDB RCSB:5afw, PDBe:5afw, PDBj:5afw
PDBsum5afw
PubMed26751641
UniProtO14646|CHD1_HUMAN Chromodomain-helicase-DNA-binding protein 1 (Gene Name=CHD1)

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