Structure of PDB 5ad3 Chain A

Receptor sequence
>5ad3A (length=127) Species: 9606 (Homo sapiens) [Search protein sequence]
SMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVK
LNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNK
PGDDIVLMAEALEKLFLQKINELPTEE
3D structure
PDB5ad3 Potent and Selective Bivalent Inhibitors of Bet Bromodomains
ChainA
Resolution1.49 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 K6K A W81 F83 N140 I146 W40 F42 N99 I105
External links
PDB RCSB:5ad3, PDBe:5ad3, PDBj:5ad3
PDBsum5ad3
PubMed27775716
UniProtO60885|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)

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