Structure of PDB 5acm Chain A

Receptor sequence
>5acmA (length=109) Species: 9606 (Homo sapiens) [Search protein sequence]
SALTQPPSASGSLGQSVTISCTGTSSDVGGYNYVSWYQQHAGKAPKVIIY
EVNKRPSGVPDRFSGSKSGNTASLTVSGLQAEDEADYYCSSYEGSDNFVF
GTGTKVTVL
3D structure
PDB5acm Inhibition by small-molecule ligands of formation of amyloid fibrils of an immunoglobulin light chain variable domain.
ChainA
Resolution1.05 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MBT A Y34 Y93 D97 F99 Y33 Y92 D96 F98
Gene Ontology
Molecular Function
GO:0003823 antigen binding
Biological Process
GO:0002250 adaptive immune response
GO:0006955 immune response
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005886 plasma membrane
GO:0019814 immunoglobulin complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5acm, PDBe:5acm, PDBj:5acm
PDBsum5acm
PubMed26576950
UniProtP01709|LV208_HUMAN Immunoglobulin lambda variable 2-8 (Gene Name=IGLV2-8)

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