Structure of PDB 5aa3 Chain A

Receptor sequence
>5aa3A (length=417) Species: 1402513 (Pseudomonas aeruginosa BWHPSA013) [Search protein sequence]
GVLRVITRNSPATYFQDRNGETGFEYELAKRFAERLGVELKIETADNLDD
LYAQLSREGGPALAAAGLTPGREDDASVRYSHTYLDVTPQIIYRNGQQRP
TRPEDLVGKRIMVLKGSSHAEQLAELKKQYPELKYEESDAVEVVDLLRMV
DVGDIDLTLVDSNELAMNQVYFPNVRVAFDFGEARGLAWALPGGDDDSLM
NEVNAFLDQAKKEGLLQRLKDRYYGHVDVLGYVGAYTFAQHLQQRLPRYE
SHFKQSGKQKDTDWRLLAAIGYQESLWQPGATSKTGVRGLMMLTNRTAQA
MGVSNRLDPKQSIQGGSKYFVQIRSELPESIKEPDRSWFALAAYNIGGAH
LEDARKMAEKEGLNPNKWLDVKKMLPRLAQKQWYAKTRYGYARGGETVHF
VQNVRRYYDILTWVTQP
3D structure
PDB5aa3 Activation by Allostery in Cell-Wall Remodeling by a Modular Membrane-Bound Lytic Transglycosylase from Pseudomonas aeruginosa.
ChainA
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.2.2.n1: peptidoglycan lytic exotransglycosylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GLU A R50 V155 L156 S159 H161 V185 L201 R8 V113 L114 S117 H119 V143 L159
Gene Ontology
Molecular Function
GO:0008933 lytic transglycosylase activity
GO:0016837 carbon-oxygen lyase activity, acting on polysaccharides
Biological Process
GO:0000270 peptidoglycan metabolic process
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5aa3, PDBe:5aa3, PDBj:5aa3
PDBsum5aa3
PubMed27618662
UniProtQ9HXN1|MLTF_PSEAE Membrane-bound lytic murein transglycosylase F (Gene Name=mltF)

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