Structure of PDB 5aa2 Chain A

Receptor sequence
>5aa2A (length=419) Species: 1402513 (Pseudomonas aeruginosa BWHPSA013) [Search protein sequence]
KEGVLRVITRNSPATYFQDRNGETGFEYELAKRFAERLGVELKIETADNL
DDLYAQLSREGGPALAAAGLTPGREDDASVRYSHTYLDVTPQIIYRNGQQ
RPTRPEDLVGKRIMVLKGSSHAEQLAELKKQYPELKYEESDAVEVVDLLR
MVDVGDIDLTLVDSNELAMNQVYFPNVRVAFDFGEARGLAWALPGGDDDS
LMNEVNAFLDQAKKEGLLQRLKDRYYGHVDVLGYVGAYTFTQHLQQRLPR
YESHFKQSGKQKDTDWRLLAAIGYQESLWQPGATSKTGVRGLMMLTNRTA
QAMGVSNRLDPKQSIQGGSKYFVQIRSELPESIKEPDRSWFALAAYNIGG
AHLEDARKMAEKEGLNPNKWLDVKKMLPRLAQKQWYAKTRYGYARGGETV
HFVQNVRRYYDILTWVTQS
3D structure
PDB5aa2 Activation by Allostery in Cell-Wall Remodeling by a Modular Membrane-Bound Lytic Transglycosylase from Pseudomonas aeruginosa.
ChainA
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.2.2.n1: peptidoglycan lytic exotransglycosylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A R37 A41 F53 E54 L77 Y81 G96 T98 V142 L143 S146 S147 H148 E150 V172 L188 D190 N192 E193 L216 Y253 R10 A14 F26 E27 L50 Y54 G69 T71 V115 L116 S119 S120 H121 E123 V145 L161 D163 N165 E166 L189 Y226
Gene Ontology
Molecular Function
GO:0008933 lytic transglycosylase activity
GO:0016837 carbon-oxygen lyase activity, acting on polysaccharides
Biological Process
GO:0000270 peptidoglycan metabolic process
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5aa2, PDBe:5aa2, PDBj:5aa2
PDBsum5aa2
PubMed27618662
UniProtQ9HXN1|MLTF_PSEAE Membrane-bound lytic murein transglycosylase F (Gene Name=mltF)

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