Structure of PDB 5aa1 Chain A

Receptor sequence
>5aa1A (length=418) Species: 1402513 (Pseudomonas aeruginosa BWHPSA013) [Search protein sequence]
EGVLRVITRNSPATYFQDRNGETGFEYELAKRFAERLGVELKIETADNLD
DLYAQLSREGGPALAAAGLTPGREDDASVRYSHTYLDVTPQIIYRNGQQR
PTRPEDLVGKRIMVLKGSSHAEQLAELKKQYPELKYEESDAVEVVDLLRM
VDVGDIDLTLVDSNELAMNQVYFPNVRVAFDFGEARGLAWALPGGDDDSL
MNEVNAFLDQAKKEGLLQRLKDRYYGHVDVLGYVGAYTFTQHLQQRLPRY
ESHFKQSGKQKDTDWRLLAAIGYQESLWQPGATSKTGVRGLMMLTNRTAQ
AMGVSNRLDPKQSIQGGSKYFVQIRSELPESIKEPDRSWFALAAYNIGGA
HLEDARKMAEKEGLNPNKWLDVKKMLPRLAQKQWYAKTRYGYARGGETVH
FVQNVRRYYDILTWVTQP
3D structure
PDB5aa1 Activation by Allostery in Cell-Wall Remodeling by a Modular Membrane-Bound Lytic Transglycosylase from Pseudomonas aeruginosa.
ChainA
Resolution2.89 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 4.2.2.n1: peptidoglycan lytic exotransglycosylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A R50 A54 F66 E67 Y94 G109 L110 T111 V155 L156 G158 S159 S160 H161 E163 V185 L201 V202 D203 N205 E206 L229 R9 A13 F25 E26 Y53 G68 L69 T70 V114 L115 G117 S118 S119 H120 E122 V144 L160 V161 D162 N164 E165 L188
Gene Ontology
Molecular Function
GO:0008933 lytic transglycosylase activity
GO:0016837 carbon-oxygen lyase activity, acting on polysaccharides
Biological Process
GO:0000270 peptidoglycan metabolic process
Cellular Component
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5aa1, PDBe:5aa1, PDBj:5aa1
PDBsum5aa1
PubMed27618662
UniProtQ9HXN1|MLTF_PSEAE Membrane-bound lytic murein transglycosylase F (Gene Name=mltF)

[Back to BioLiP]