Structure of PDB 5a31 Chain A

Receptor sequence
>5a31A (length=1441) Species: 9606 (Homo sapiens) [Search protein sequence]
MIAARDLQEFVPFGRDHCKHHPNALNLQLRQLQPASEAAAAAGAAAAAKE
SWQLRKAVSEIGEDVDYDEELYVAGNMVIWSKGSKSQALAVYKAFTVDSP
VQQALWCDFIISEVEKCICILQSSCINMHSIEGKDYIASLPFQVANVWPT
KYGLLFERSPLPTMFSMLHPLDEITPLVCKAQYVVDHAMKIVFLNTDPSI
VMTYDAVQNVHSVWTLRRVKAEEEAAAAAAAAAGGFAAAAPIVPELCIDH
LWAAAQASKVFITSDLCGQKFLCFLVESQLQLRCVKFQESTALIFGSVTN
IPAKDAAPVEKIDTMLVLEGSGNLVLYTGVVRVGKVFIPATYIHSIRDPV
HNRVTLELSNGSMVRITIPEIATSELVQTCLQAIKFILPKEIAVQMLVKW
YNVHSAPGGASYHSEWNLFVTCLMNMMGYTHIPAIFFVLHLVYEELKLNT
LMGEGICSLVELLVQLARDLKLGPYVDHYYRDYPTLASEPPSIYQWVSSC
LKGEGAPPYPYLPGICERSRLVVLSIALYILSSLAERLVVWMTNVGFILR
DLETLPFGIALPIRDAIYHCREQPASDWPEAVCLLIGRQDLSAADDGMND
MNHEVMSLIWSEDLRVQDVRRLLQSAHPVRVNVVQYPELSEHEFIEEKEN
RLLQLCQRTMALPVGRGMFTLFSYHPVPTEPLPIPKLNLTGRAPPRNTTV
DLNSGNIDVPPNMTSWASFHNGVAAGLKIAPASQIDSAWIVYNKPKHAEL
ANEYAGFLMALGLNGHLTKLATLNIHDYLTKGHEMTSIGLLLGVSAAKLG
TMDMSITRLLSIHIPALLPPTSTELDVPHNVQVAAVVGIGLVYQGTAHRH
TAEVLLAEIGRPPGPEMEYATDRESYSLAAGLALGMVCLGHGSNLIGMSA
LNVPEQLYQYMVGGHSPSYQIKEGDTLNVDVTCPGATLALAMIYLKTNNR
SIADWLRAPDTMYLLDFVKPEFLLLRTLARCLILWDDILPNSKWVDSNVP
QIIRENLNLETLSQAHVYIIAGACLSLGFRFAGSENLSAFNCLHKFAKDF
MTYLSAPNASVTGPHNLETCLSVVLLSLAMVMAGSGNLKVLQLCRFLHMK
TGGEMNYGFHLAHHMALGLLFLGGGRYSLSTSNSSIAALLCALYPHFPAH
STDNRYHLQALRHLYVLAAEPRLLVPVDVDTNTPCYALLEVLYKGTQWYE
QTKEELMAPTLLPELHLLKQIKVKGPRYWELLIDLTQHLKSILSKDGVLY
VKLRAGQLSYKEDASEARAFKSAFTSDPALLSFAEYFCKPTVNMGQKQEI
LDLFSSVLYECVTQETPEMLPAYIAMDQAIRRLGRREMSETSELWQIKLV
LEFFSSRSHQFMNSEFLPVVKCTIDNTLDQWLQVGGDMCVHAYLSPLESQ
LSMLACFAVYHSVPAPAAAAAAAAAAAAAAAAAAAAAAAAA
3D structure
PDB5a31 Atomic Structure of the Apc/C and its Mechanism of Protein Ubiquitination.
ChainA
Resolution4.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A E1480 N1481 L1482 E1649 E1035 N1036 L1037 E1204
BS02 peptide A S1317 N1320 S899 N902
Gene Ontology
Cellular Component
GO:0005680 anaphase-promoting complex

View graph for
Cellular Component
External links
PDB RCSB:5a31, PDBe:5a31, PDBj:5a31
PDBsum5a31
PubMed26083744
UniProtQ9H1A4|APC1_HUMAN Anaphase-promoting complex subunit 1 (Gene Name=ANAPC1)

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